The Clinical Approach to Anemia
A three-part interactive lecture — from the definition of anemia at altitude, through classification, to the red cell under attack. Rebuilt as living diagrams you can touch.
Anemia is not a number but a state — of decreased tissue oxygenation. This lecture builds the clinician’s approach from first principles, then follows the red cell into the two great families of hemolysis. Each concept is an interactive figure: drag the altitude to move the anemia cutoff, lock the hepcidin iron gate, cleave a von Willebrand multimer, or lyse cells along an osmotic-fragility curve.
The Clinical Approach
Definition at altitude, kinetic & morphologic classification, the microcytic workup, and the hepcidin iron gate.
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The Red Cell Under Attack
Extravascular vs intravascular hemolysis, the lab panel, AIHA & the Coombs test, MAHA, and TTP.
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The Inside Job
Membrane (HS + osmotic fragility), enzyme (G6PD), and cargo (thalassemia, sickle cell) defects.
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