Evidence-based reviews

Risk factors for VTE, prevalence of hereditary thrombophilias in healthy Saudis and in tested populations, why natural-anticoagulant testing is unreliable, antiphospholipid syndrome, whether testing reduces recurrence, and a comprehensive review of guidelines on thrombophilia testing with a proposed local Saudi approach · Haematology · Thrombophilia

A century of the procedure from Ghedini and the sternal needle to the Jamshidi needle and powered drivers; indications, core length and the operator, analgesia, bleeding risk, and CT, fluoroscopic, ultrasound and PET/CT-guided biopsy in the difficult patient · Haematology · Interventional radiology

How drugs lower the platelet count and how causality is judged; mechanisms, recognition, laboratory confirmation and management; heparin-induced thrombocytopenia; and the implicated drugs by system — cardiovascular, rheumatology and immunology, anti-infectives, neurology and psychiatry, oncology, gastrointestinal, analgesics, anaesthesia and intensive care, vaccines · Haematology · Clinical pharmacology

Kinds of genetic lesion and the pathways they hit; clonal haematopoiesis and germline predisposition; AML, MDS, myeloproliferative neoplasms and CML; lymphoblastic leukaemia and CLL; the lymphomas and myeloma; WHO-HAEM5 and ICC 2022, ELN 2022, IPSS-M, clonal evolution and the targeted drugs · Haematology · Genetics

Combined and progestogen-only contraception, thrombophilia, menopausal hormone therapy, pregnancy and the postpartum period, recurrence, hormones and menstrual bleeding during anticoagulation, and the management and long-term sequelae of hormone-associated cerebral venous thrombosis · Haematology · Women's health

Epidemiology, diagnosis and treatment — from the two heparin trials to direct oral anticoagulants, endovascular therapy, decompressive surgery and vaccine-induced immune thrombotic thrombocytopenia · Haematology · Neurology