Three parts, read in any order. Part One works through the diseases system by system, each case following one patient from the focused history to the viva questions. Part Two starts instead from the presenting problem — the jaundiced patient, the patient in shock — where the diagnosis is what you are trying to reach rather than what you were given. Part Three is about reading the investigation itself.
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Front Matter · How to Use This Casebook
Part One · Disease Cases by System
Cases 1–8
The Respiratory Block
Pneumonia, asthma, COPD, suppurative lung disease, hypercapnic failure, pleural effusion, lung cancer and pulmonary hypertension.
Cases 9–18
The Cardiology Block
Rheumatic fever and mitral stenosis, STEMI, decompensated heart failure, endocarditis, hypertension, valve disease, pericardial disease and the cardiomyopathies.
Cases 19–27
The Endocrinology Block
DKA, type 2 diabetes and its chronic complications, HHS, thyrotoxicosis, hypercalcaemia, pituitary and adrenal disorders, and lipids.
Cases 28–33
The Nephrology Block
Acute kidney injury, chronic kidney disease, acid–base disorders, hyponatraemia, urinary tract infection and glomerulonephritis.
Cases 34–40
The Gastroenterology Block
Peptic ulcer disease, acute and chronic viral hepatitis, decompensated cirrhosis, upper GI bleeding, inflammatory bowel disease and hepatocellular carcinoma.
Cases 41–48
The Infectious Diseases Block
Brucellosis, malaria, tuberculosis, bacterial meningitis, HIV, pneumonia in the immunocompromised host, encephalitis, and the principles of antimicrobial use.
Cases 49–57
The Haematology Block
Microcytic, macrocytic and haemolytic anaemia, sickle cell disease and thalassaemia, the bleeding patient, the acute and chronic leukaemias, lymphoma, myeloma and the myeloproliferative neoplasms.
Cases 58–63
The Rheumatology Block
Rheumatoid arthritis, systemic lupus erythematosus, axial spondyloarthritis, vasculitis, crystal arthropathy and antiphospholipid syndrome.
Cases 64–69
The Neurology Block
Acute ischaemic stroke, seizures and status epilepticus, acute neuromuscular weakness, peripheral neuropathy, myelopathy and demyelination, and the extrapyramidal disorders.
Cases 70–79
Dermatology and Envenomation
Skin signs of systemic disease, eczema, snake, scorpion and spider envenomation, cutaneous infections and infestations, psoriasis, the blistering and drug emergencies, skin tumours, and sexually transmitted infections.